Understanding the concept of genetics needs to be balanced with high-level thinking and excellent metacognitive skills. However, efforts to measure the correlation between these two factors are still carried out partially. This study aims to determine the correlation between critical thinking, metacognitive skills, and cognitive learning outcomes in genetic. This study is correlational that measures the relationship between variables of students’ critical thinking skills (X1), metacognitive skills (X2), and students’ cognitive learning outcomes (Y).